Which type of lymphoma is the most common form of non-Hodgkin lymphoma in adults?

Diffuse large B-cell lymphoma (DLBCL) is the most common form of non-Hodgkin lymphoma in adults, accounting for approximately 30% of all non-Hodgkin lymphoma cases. This subtype is characterized by the rapid growth of large B lymphocytes and can arise in a variety of anatomical locations, including lymph nodes and extranodal sites. DLBCL often presents in a more aggressive manner, leading to significant clinical manifestations such as lymphadenopathy, fevers, night sweats, and weight loss.

The management of DLBCL typically involves a combination of chemotherapy and, in some cases, immunotherapy, demonstrating its importance in the landscape of hematologic malignancies. Its prevalence and treatment approach underscore the need for clinicians to be well-acquainted with DLBCL when addressing non-Hodgkin lymphoma in adult patients.