Which organism is commonly responsible for acute infectious lymphangitis?

Acute infectious lymphangitis is commonly caused by Streptococcus pyogenes, a β-hemolytic streptococcus known for its role in skin and soft tissue infections, particularly following skin breaks. This organism is capable of rapidly spreading through the lymphatic system, leading to the characteristic symptoms of lymphangitis such as red streaking along the lymphatic vessels, fever, and local pain or tenderness. In some cases, Methicillin-sensitive Staphylococcus aureus (MSSA) can also be involved in the condition, particularly in patients with skin infections or other predisposing factors.

The pathogenesis involves bacterial entry through a cut or abrasion, triggering an inflammatory response in the lymphatic channels. Streptococcus pyogenes is particularly efficient at this, as it can adhere to and invade host cells, causing necrosis and suppuration, ultimately leading to lymphatic inflammation.

While other organisms such as Escherichia coli, Staphylococcus epidermidis, and Clostridium perfringens may be involved in different types of infections or conditions, they are not typical pathogens associated with acute infectious lymphangitis. E. coli is more often implicated in urinary tract infections or intestinal diseases, Staphylococcus epidermidis is typically a skin