Which of the following symptoms is NOT typically associated with Primary Biliary Cholangitis (PBC)?

Primary Biliary Cholangitis (PBC) is an autoimmune liver disease characterized by the destruction of the small bile ducts within the liver. This condition is commonly associated with a range of signs and symptoms linked to cholestasis and liver dysfunction.

Jaundice, or yellowing of the skin and eyes, is a common manifestation in PBC as the disease progresses, leading to an accumulation of bilirubin due to impaired bile flow. Xanthelasma, which are yellowish lesions on the eyelids, often occur in patients with PBC due to associated lipid abnormalities. Chronic fatigue is another hallmark symptom of PBC, affecting a significant number of patients and heavily impacting their quality of life.

In contrast, hematuria, or blood in the urine, is not a symptom associated with PBC. While it can indicate issues related to the kidneys or urinary tract rather than liver disease, it does not align with the common clinical presentation of PBC. Therefore, this option stands out as the incorrect association within the context of this condition.