Which of the following is not a typical characteristic of hyper IgE syndrome?

Hyper IgE syndrome, also known as Job's syndrome, is characterized by a specific immune deficiency that leads to elevated levels of immunoglobulin E (IgE). Patients with this condition often present with several hallmark features, which include recurrent infections, such as pneumonia, due to a defect in the immune system's ability to combat specific pathogens. Additionally, they commonly experience skin manifestations, including eczema and recurrent skin abscesses, as a result of impaired neutrophil function.

The defining characteristic of hyper IgE syndrome is high serum IgE levels, which are significantly elevated compared to normal levels. Therefore, low serum IgE levels are not associated with this disorder and make this choice the correct answer as the item that does not align with the common characteristics found in patients suffering from hyper IgE syndrome. Recognizing these features is crucial for understanding the clinical presentation and guiding management for individuals with this complex immunological condition.