Which of the following conditions presents commonly with fractures and osteoporosis without metabolic changes?

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The condition that presents commonly with fractures and osteoporosis without metabolic changes is osteoporosis. Osteoporosis is characterized by a decrease in bone density and mass, leading to an increased risk of fractures, particularly in areas such as the hip, spine, and wrist. This condition primarily results from an imbalance between bone resorption and bone formation, which can be influenced by factors such as aging, sex (more common in postmenopausal women), lack of physical activity, and nutritional deficiencies (e.g., insufficient calcium or vitamin D).

Unlike other conditions listed, osteoporosis typically does not involve alterations in serum calcium, phosphate, or parathyroid hormone levels that are characteristic of metabolic bone diseases. Instead, osteoporosis is generally considered a skeletal disorder without further metabolic disturbances, making it a distinct entity compared to conditions like hypoparathyroidism or rickets, which feature specific metabolic derangements associated with calcium and phosphate metabolism. Therefore, when assessing for fractures and osteoporosis without metabolic changes, osteoporosis is the primary diagnosis to consider.

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