Which condition is associated with swelling and tenderness at the anteromedial aspect of the knee?

The condition associated with swelling and tenderness at the anteromedial aspect of the knee is pes anserine bursitis. This condition arises when the bursa located beneath the pes anserinus—a site of attachment for the tendons of the sartorius, gracilis, and semitendinosus muscles—becomes inflamed. The pes anserinus is situated on the anteromedial aspect of the tibia, and thus, when it is inflamed, individuals often report localized swelling and tenderness in this area.

Patients typically present with pain when touching the region below the knee joint or during activities that put stress on the knee. It's commonly seen in individuals who engage in repetitive activities involving knee flexion, such as runners or overweight individuals.

The other conditions mentioned may present with different symptoms or in different areas of the knee. Patella bursitis usually presents with swelling over the front of the knee, while iliotibial (IT) band syndrome is characterized by lateral knee pain. Quadriceps tendonitis would generally be associated with pain around the patella and the front part of the knee, potentially without the specific anteromedial tenderness seen in pes anserine bursitis.