What is the primary treatment for Dressler syndrome?

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The primary treatment for Dressler syndrome, which is a form of post-myocardial infarction pericarditis, typically involves the use of high doses of aspirin combined with colchicine. Aspirin acts as an anti-inflammatory agent to alleviate pain and reduce inflammation of the pericardium, while colchicine serves to independently decrease inflammation and prevent recurrent episodes of pericarditis. This combination has been shown to be effective at improving symptoms and reducing the risk of recurrence.

It is important to note that while non-steroidal anti-inflammatory drugs (NSAIDs) are often used in the management of pericarditis, colchicine provides additional benefits that are particularly valuable in the context of Dressler syndrome. High-dose ibuprofen or prednisone, though sometimes utilized in pericarditis, are not considered the primary treatment modalities in this scenario due to the benefits of the combination of aspirin and colchicine.

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