What is the mechanism of action of Saw Palmetto in the treatment of BPH?

Saw Palmetto is primarily used as a complementary therapy in the treatment of benign prostatic hyperplasia (BPH). Its mechanism of action involves the inhibition of 5-alpha reductase, an enzyme that converts testosterone into dihydrotestosterone (DHT). DHT is the more potent androgen that plays a significant role in the development and enlargement of prostate tissue. By inhibiting this enzyme, Saw Palmetto helps to reduce the levels of DHT, which can lead to a decrease in prostate size and an improvement in urinary symptoms associated with BPH.

The rationale for using Saw Palmetto as a treatment is grounded in the understanding that higher levels of DHT contribute to prostate enlargement, which is a key factor in BPH. Therefore, by addressing this specific biochemical pathway, Saw Palmetto may assist in managing symptoms and improving quality of life for individuals affected by BPH.