What is the empiric treatment for acute infectious lymphangitis?

The empiric treatment for acute infectious lymphangitis typically focuses on the anticipated pathogens, which primarily include Streptococcus species and Staphylococcus aureus. Cephalexin, a first-generation cephalosporin, is particularly effective against these organisms, making it a suitable choice for treating uncomplicated infections like lymphangitis.

Cephalexin is effective for both gram-positive cocci and some gram-negative bacteria, which aligns with the infectious etiology often observed in cases of lymphangitis. Its mechanism of action involves inhibiting bacterial cell wall synthesis, leading to cell lysis and death, which is crucial in managing such infections.

Other options such as amoxicillin, ceftriaxone, and clindamycin have their indications and benefits, but they may not be as focused or effective for the common pathogens associated with acute infectious lymphangitis. For instance, amoxicillin primarily targets certain gram-positive and gram-negative bacteria but may not provide adequate coverage for all strains of Staphylococcus. Ceftriaxone, a broad-spectrum cephalosporin, is used for more severe infections or when polymicrobial coverage is needed. Clindamycin, while effective against anaerobes and some gram-positive bacteria, is not as