What is a common symptom of erythema nodosum?

Erythema nodosum is characterized by the presence of painful, erythematous nodules that typically appear on the lower legs. These nodules are a result of inflammation in the subcutaneous tissue and are commonly associated with a delayed hypersensitivity reaction. While fever, joint pain, and itching can occur in conjunction with various inflammatory conditions, the hallmark symptom of erythema nodosum specifically is the development of distinctive skin nodules. This key presentation helps differentiate erythema nodosum from other dermatological or systemic conditions where other symptoms might predominate.