What is a common symptom of Clostridium difficile infection?

Clostridium difficile infection is primarily known for causing gastrointestinal symptoms, with watery diarrhea being the most common and distinguishing symptom. The infection often occurs after antibiotic use, which disrupts the normal gut flora, allowing C. difficile to proliferate and produce toxins, leading to inflammation of the colon and diarrhea. This diarrhea can be profuse and watery, sometimes containing blood or mucus, and is a hallmark feature of the infection.

Unlike the other symptoms listed, watery diarrhea directly correlates with the pathogenic effects of C. difficile in the intestines. Chest pain, constipation, and fever and chills can be associated with various medical conditions but are not specific to C. difficile infection. The presence of watery diarrhea is a critical indicator that points towards a diagnosis of Clostridium difficile infection, guiding further clinical management and treatment.