What initial lab analyses should be conducted during the first trimester of pregnancy?

The recommended initial lab analyses during the first trimester of pregnancy include a complete blood count (CBC), blood typing including ABO and Rh type, screening for hepatitis B, syphilis, human immunodeficiency virus (HIV), and rubella immunity.

A CBC is important for assessing the maternal blood count to check for anemia and overall health status. Testing for ABO and Rh factor helps determine the risk of hemolytic disease of the newborn, especially if the mother is Rh-negative. Screening for hepatitis B is crucial because if a mother is positive, interventions can be taken to prevent transmission to the infant. Syphilis screening is part of standard prenatal care to manage any infections early on, as untreated syphilis can lead to serious complications. Finally, rubella immunity status is tested to protect future pregnancies, as rubella infection in the first trimester can cause significant fetal morbidity and mortality.

Other options do not encompass the full range of initial screenings considered standard practice in the first trimester. For example, while HIV and rubella are included in some choices, others lack important tests like Hepatitis B and syphilis. Comprehensive initial screenings are essential for ensuring maternal and fetal health, guiding appropriate interventions early on in the pregnancy.