What indicates the recovery stage in Hepatitis B serology?

The recovery stage in Hepatitis B serology is indicated by the presence of Anti-HB surface IgG. This antibody emerges as the body responds to the Hepatitis B virus after the initial infection. During this stage, the person is effectively clearing the virus from their system, and the presence of Anti-HB surface IgG suggests that the immune system has developed a memory response to the virus.

In addition to indicating recovery, the presence of Anti-HB surface IgG is also a marker of immunity, which occurs after acute Hepatitis B infection has resolved or after vaccination. It is significant in a clinical context as it helps to determine whether a person is susceptible to re-infection or has developed immunity against the virus.

The other choices, such as HB surface antigen, indicate active viral replication and infection, while Anti-HB core IgG may show past infection but does not specifically indicate recovery status. Anti-HB e IgG could be present during chronic infection but also may indicate recovery depending on the clinical context, but it is Anti-HB surface IgG that directly signifies recovery and a transition to an immune stage.