What condition is characterized by linear ulcers in the esophagus of immunocompromised patients, as seen on EGD?

The condition characterized by linear ulcers in the esophagus of immunocompromised patients, as observed during an esophagogastroduodenoscopy (EGD), is indeed associated with cytomegalovirus (CMV) esophagitis. CMV esophagitis often presents with significant mucosal injury, leading to the formation of these linear ulcers, particularly in individuals with weakened immune systems, such as those with HIV/AIDS or those on immunosuppressive therapy.

The ulcers are typically seen as well-defined linear lesions within the esophagus, setting this condition apart from other esophageal diseases. Herpes esophagitis, for instance, usually presents with multiple small vesicular lesions and superficial ulcers rather than the elongated ulcers typical of CMV. In contrast, candidiasis typically presents with white plaques or a coating on the esophageal mucosa, and while bacterial esophagitis may complicate existing conditions, it does not commonly produce the characteristic linear ulcers associated with CMV. Understanding these key features helps in accurately diagnosing and managing esophageal conditions, particularly in immunocompromised patients.